Symbol
Name
ID

Pepd
peptidase D
MGI:97542

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Increased circulating antibody level	Splenomegaly	Recurrent cystitis	Abnormality of the immune system	Crusting erythematous dermatitis	Eczematoid dermatitis	Recurrent pneumonia	Systemic lupus erythematosus	Asthma	Recurrent infections	Recurrent respiratory infections
Disease(s) Associated with PEPD
prolidase deficiency

Mouse Phenotypes

decreased immature B cell number

decreased transitional stage T1 B cell number

decreased B-2 B cell number

decreased follicular B cell number

decreased B cell number

increased memory-marker NK cell number

decreased CD5-positive Ly6C-positive T cell number

increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number

increased CD4-positive, alpha-beta T cell number

increased effector memory CD8-positive, alpha-beta T cell number

increased memory-marker CD4-negative NK T cell number

decreased Ly6C-positive NK T cell number

increased effector memory T-helper cell number

increased leukocyte cell number

enlarged lymph nodes

Availability

Mouse Genotype

Pepd^{tm1a(KOMP)Wtsi}/Pepd^{tm1a(KOMP)Wtsi}

Pepd^{tm1b(KOMP)Wtsi}/Pepd^{tm1b(KOMP)Wtsi}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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